Albumin-Bound Injection
Drug-binding albumin nanotechnology mainly uses albumin as a carrier material to realize the delivery of water-insoluble drugs with high protein binding rate. It is biocompatible, non-toxic, non-immunogenic, etc. Nanomedicines using it as a carrier have unique advantages in tumor targeting.
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Experimental parameters
| Dissolution apparatus | RT7 Flow-Through Cell Dissolution System |
| Type of Flow-Through Cell | Cell for 22.6mm |
| Temperature | 37℃± 0.5℃ |
| Sample volume | 1 mL |
| Model | Closed-loop |
| Pulse | 0 Hz |
Experimental Result
①Reproducibility: The RSD range of Sample 1 was 1.42~6.93% while Sample 2 was 1.53~2.06%.
②Distinguish: This method has good discrimination between Sample 1 and Sample 2.
CONCLUSION: RT700 provides good reproducibility and distinguish for in vitro dissolution testing of albumin-bound injection.
